Aug 28, 2023An investigational in vivo base editing medicine targeting ANGPTL3, VERVE-201, achieves potent and LDLR-independent liver editing in mouse models ESC VERVE-201 2023 ANGPTL3
May 26, 2023Developing ‘once-and-done’ gene editing medicines to treat cardiovascular disease EAS VERVE-101, VERVE-201, GalNAc-LNP 2023 ANGPTL3, PCSK9
Mar 05, 2023Preclinical Data Supporting Potential Efficacy of VERVE-201, an Investigational Base Editing Medicine Targeting ANGPTL3 ACC VERVE-201, GalNAc-LNP 2023 ANGPTL3
Nov 06, 2022VERVE-101 – an investigational single- course gene editing medicine targeting PCSK9 – durably and potently lowers PCSK9 and LDL-C concentrations in non-human primates AHA VERVE-101 2022 PCSK9
Aug 29, 2022An in vivo CRISPR base editing therapy to inactivate ANGPTL3: nomination of a development candidate for VERVE-201 [presentation] ESC VERVE-201, GalNAc-LNP 2022 ANGPTL3
Aug 29, 2022An in vivo CRISPR base editing therapy to inactivate ANGPTL3: nomination of a development candidate for VERVE-201 [poster] ESC VERVE-201, GalNAc-LNP 2022 ANGPTL3
May 16, 2022Disrupting the care of cardiovascular disease with single-course gene editing medicines ASGCT VERVE-101, VERVE-201, GalNAc-LNP 2022 ANGPTL3, PCSK9